Author's research blog for the medical science techno-thriller A REMEDY FOR DEATH

REMEDY new FRONT BLACK May 28 2014

It's said that we only go around once in life . . . at least that's the way it's always been.

But what if? What if the terms of life have changed . . . for an elite, self-selected few?

What if today's emerging bio-tech and regenerative medical technologies—including the ability to regrow and implant body parts and organs—offer the chance for another whole go-round in life to a select, secretive few . . . a chance to come back, as one of them puts it, into “healthy, horny 21-year old bodies complete with all our accumulated savvy from this lifetime”?

A REMEDY FOR DEATH–Frankenstein and eternal youth in the age of bio-tech, tissue engineering, cloning, and regenerative medicine.

What if the project is almost successful . . . but opens dangerous doors . . . doors that cannot be closed?

 

A REMEDY FOR DEATH is fiction, but based on a great deal of keeping-up with what's happening in the various fields that make up what we know as bio-tech, regenerative medicine, and the role of the human mind. I'll be sharing some of that here on this blog, to which I'll be adding other items that I haven't yet posted  . . . as well as news of discoveries to come.

 

To order A Remedy for Death as ebook or pbook via Amazon

To order as ebook or pbook from other retailers, using universal link

To read sample chapters of A REMEDY FOR DEATH 

To view the book trailer "RADICAL LIFE EXTENSION and A REMEDY FOR DEATH"

 

And  . . . to read my blog posts and other research materials, continue below, or check the sidebars here for "Recent Posts" and "Categories".  Here a few to get you started:

 

Tech titans’ latest: Project Defy Death. Washington Post, page 1 above the fold, April 5, 2015;

http://www.washingtonpost.com/sf/national/2015/04/04/tech-titans-latest-project-defy-death/#

 

Silicon Valley is trying to make humans immortal—and finding some success.  Newsweek cover story, Mar 15, 2015;

  http://www.newsweek.com/2015/03/13/silicon-valley-trying-make-humans-immortal-and-finding-some-success-311402.html  

 

Google ventures and the search for immortalityBloombergBusiness, March 9, 2015;

http://www.bloomberg.com/news/articles/2015-03-09/google-ventures-bill-maris-investing-in-idea-of-living-to-500

 

What if aging is nothing but a mind-set?  New York Times Magazine. October 26, 2014;

http://www.nytimes.com/2014/10/26/magazine/what-if-age-is-nothing-but-a-mind-set.html?_r=2

 

The Forever Pill. Cover story, Bloomberg BusinessWeek, February 18, 2015;

http://www.bloomberg.com/news/features/2015-02-12/does-a-real-anti-aging-pill-already-exist-

 

Can Google solve death?   Cover story, Time, September 30, 2014

http://content.time.com/time/magazine/article/0,9171,2152422,00.html#ixzz2fMq3cHhF

 

Live forever: Scientists say they’ll soon extend life “well beyond” 120. The Guardian, January 11, 2015;  http://www.theguardian.com/science/2015/jan/11/-sp-live-forever-extend-life-calico-google-longevity

 

Custom organs, printed to order. Nova Next, March 18, 2015.

http://www.pbs.org/wgbh/nova/next/body/3d-printed-organs/

 

This baby could live to be 142 years old: Dispatches from the frontiers of longevity. Time, cover story, February 23-March 2 2015

http://backissues.time.com/storefront/2015/this-baby-could-live-to-be-142-years-old/prodTD20150223.html

 

Radical Life Extension getting more mainsteam and getting more funding. NextBigFuture.com, January 11, 2015

http://www.nytimes.com/2014/10/26/magazine/what-if-age-is-nothing-but-a-mind-set.html?_r=2

 

 

 


The exercise pill! A synthetic biology triumph in the making! A bio-engineered ticket to the Fountain of Youth!

At last!  Now that the Baby Boomers and even the Millennials are just beginning to think those thoughts of "Am I getting old? Not me!"  Now comes “Compound 14”—a recently discovered molecule triggers  “a chain reaction of events in the cell that . . . well, to make  long technical story short, tricks human body cells into “thinking” the body has just been for a good, solid workout.

Or, put differently, “ZMP” the master regulator, sends the signal that activates “AMPK” the cells’ central energy censor. Got that?

Bottom line: alas, Compound 14 isn’t for sale yet at the corner drugstore, but the work, headed by Ali Tavassoli, a professor of chemical biology, and Felino Cagampang, an associate professor in integrative physiology, is underway at the University of Southhampton in England.

The study, published in the journal, Chemistry and Biology, details how Compound 14 was given to two groups of mice, and the fat, chubby group lost five percent of body weight after receiving it for seven days.

Is that not a big step toward the Fountain of Youth (at least for mice)!

Who knows what wonders await us, thanks to the tools of bio-engineering and synthetic biology . . . provided somehow we can slow the human aging process so we can all hang around until those wonders do arrive.

If you're not ready for the complete paper in the scientific journal, check out this article in the Washington Post by Ariana Eunjung Cha


Big step taken toward achieving the "Holy Grail" of regenerative medicine

British scientists have now taken cells from a mouse embryo and, "flipped a genetic switch" in the DNA, and then injected the product into another mouse with a defective organ, where those injected cells grew into the whole organ of another mouse. (In that case, it was the thymus, which relates to  the immune system.)

The work was done under the lead of Prof. Clare Blackburn, of the Medical Research Council / Center for Regenerative Medicine at the University of Edinburgh. The most complete article I've found is by Rebecca Smith, medical editor of London's Daily TelegraphHere's the link

You can also find a shorter piece by Pranav Dixit in Gizmodo. Here's that link

 If you've keeping up with this blog, you'll have seen other stories about growing replacement organs. So what's distinctive about this?  This is reportedly the first time the organ has been grown inside the target creature.

When can we expect to find something like this happening for humans?  According to one scientist, maybe ten years and tens of millions of pounds for research. But by then, odds are the products will relate to other elements in the quest for radical life extension.