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January 2012
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September 2012

"Stem cells help regrow damaged heart tissue" --- USA Today

Actually, the same research published in the British medical journal The Lancet, appeared in both USA Today and the British newspaper,  The Independent by John Von Radowitz.

Here's the link to the   USA Today article by Liz Szabo.

Both articles report on the same findings, though with different details.

 


Hyperbaric oxygen chambers-- another use, this by Olympic swimmer Michael Phelps

We recently examined here the use of hyperbaric oxygen chambers as a tool to aid recuperation from  slow-to-heal wounds and other health conditions.  Link to that blog post:  "Hyperbaric oxygen chambers--- nowadays not just science fiction."

That was in the context of the role hyperbaric oxygen chambers play in my  medical techno-thriller,  A REMEDY FOR DEATH.

Today I came on another use of hyperbaric chambers, this in both USA Today and in more detail in Toronto's Globe and Mail.

American Olympic swimmer Michael Phelps 16 medals), has been "sleeping at 8,000 feet every night," in a hyperbaric chamber.

According to the Globe and Mail article, these chambers "are used by many athletes to replicate high-altitude conditions and boost levels of oxygen-rich blood cells."  Link to the article by Rachel Cohen in the Globe and Mail

What's particularly interesting to me is that for healing purposes, patients enter the hyperbaric chambers and go as if underwater, where air pressure is heavier.  Phelps and other athletes do the opposite: instead, they use the tanks set to simulate going up where the air is thinner.  That simulated altitude changes the body make-up, stimulating the growth of red blood cells.

And bear in mind the rumor that singer Michael Jackson slept in a hyperbaric chamber to slow the aging process.  Dr. Timothy Adkins (mentioned in my previous post, above) pointed out that he could not have slept all night in a chamber set to simulate underwater pressure: that would have resulted in damage and possible convulsions.

But --- and it is still a rumor, bear in mind --- perhaps Mr. Jackson, like Mr. Phelps, slept in a hyperbaric chamber set to a thinner atmosphere, as if on a mountain. Who knows?


"Cloning scientists create human brain cells," reports the London Observer

 "We can take a skin sample, make stem cells from it and then direct these stem cells to grow into brain cells. Essentially, we are turning a person's skin cells into brain. We are making cells that were previously inaccessible. And we could do that in future for the liver, the heart and other organs on which it is very difficult to carry out biopsies."

--- This from Professor Charles ffrench-Constant, director of the Roslin Institue at Edinburgh University, where sheep Dolly was cloned 16 years ago.

This work does not rely on using embryos at all; instead the cloning or regeneration comes from scraps of a patient's own skin.

Sounds like something from a Michael Crichton thriller? I hope so, but it's not from Crichton's, but rather from one of mine.

I won't spoil the plot of my speculative thriller, A REMEDY FOR DEATH, by pointing out how this work ties in with what is done in the fictional clinic in the book. But it does, and that part of the book was written way back even before Dolly saw the light of day.

The article is by Robin McKie in the Observer of January 28, 2012. Here's the link


Hyperbaric oxygen chambers--- nowadays not just science fiction.

Science fiction that's not fictional, technology that probably seemed far-out a couple or so decades back but is everyday use now.  I'm referring to hyperbaric oxygen chambers.

As hyperbaric chambers and hyperbaric oxygen therapy play key parts in my medical techno-thriller, A REMEDY FOR DEATH, I took advantage of an opportunity recently to visit (as an observer, not a patient) the Center for Wound Care & Hyperbaric Medicine, a part of the Sebastian River Medical Center in Sebastian, Florida. 

I came away with some photos and info I hadn't previously known, and thought this would be a good place to share as background to readers of A REMEDY FOR DEATH.

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 Before there was hyperbaric oxygen therapy to stimulate healing, there were decompression tanks for divers. Initially, decompression tanks were used with divers suffering from the bends, though more recently have been used to reduce the amount of underwater decompression needed from deep dives. (It's a lot more comfortable to sit or lie in a decompression chamber than to hang on a rope in cold water.)

The primary objective in using  hyperbaric oxygen therapy for a patient is to increase the concentration of oxygen in the blood, as a way of promoting healing. For that reason, a lot of the patients attending the Sebastian Center for Wound Care & Hyperbaric Medicine suffer from diabetic wounds or other injuries that have bneen slow to heal.

Put them in a chamber, pump up the concentration to maybe two atmospheres or so (around what you'd be experiencing as a scuba diver 30-50 feet underwater), then increase the oxygen to 100% from its normal range when mixed with outside air, and healing significantly speeds up. Though, to qualify that, it may take 10, 30 or more sessions in the tank for the desired breakthrough.

Each "dive" lasts from one to about two and a  half hours. (The term "dive" comes from the old use for divers. Besides, if I were a patient, I think I'd rather brag to the gang down at the bowling alley that "I'm going to take a dive tomorrow", than say the ho-hum "off to therapy.")

While in that "dive," the patient lies on a comfortable bed, and can read or watch TV. (But definitely not smoke! Remember how bad things happen when pure oxygen and flames, or even sparks, get together.)  For that same reason-- to avoid any chance of a spark -- the maintenance staff uses special mops and solvents.

Here's another shot of a hyperbaric chamber, this time with the hatch sealed.  The tanks used here are open and bright, so patients don't risk the claustrophobic sense in other "tubes" such as MRI.

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I said the primary objective in using hyperbaric therapy is to speed healing, that is, helping tissues knit together more rapidly.

But there are other uses, including to help the recovery of victims of stroke or Traumatic Brain Injuries (TBI).  It seems that most of the more visionary experimental work has to be done outside the United States, because of our slow-to-change regulatory mode.

There was a rumor that singer Michael Jackson slept in a hyperbaric chamber in the hopes of staying young. Rumor or true, who knows.  But there is research being done on that now--- can hyperbaric oxygen therapy slow aging?

My thanks to Timothy G. Adkins, M.D., Medical Director at the Center for Wound Care & Hyperbaric Medicine, part of the Sebastian River Medical Center, Sebastian, FL.  Oh, as to the question, What does it feel like to be in a hyperbaric chamber breathing oxygen?  According to Dr. Adkins, it doesn't feel any different than breathing normal air at normal pressure.